Here are my favorite picks for anime like Last Exile: Ginyoku no Fam. Keep in mind the list is in no particular order. Enjoy the recommendations!
In the far future, the elevated irradiation from the sun has destroyed the environment of the earth and the birthrate of humans has drastically decreased. The government controls society with an army of cloned soldiers called “Ideal Children (IC)”. Sam Coyne is a trader in a desert. One day, he saves a beautiful woman Maya, who has been chased by Theseus, a corps of IC. He shelters her in his trade ship, but the destroyers of Theseus surround Sam and Maya. (Source: MyAnimeList)
The war between the Levamme Empire and the Amatsukami Imperium has been raging for years. In the midst of this struggle, the prince of the Levamme Empire declares his love for Juana del Moral and vows to end the war in one year, as part of his marriage proposal. When the Amatsukami catch wind of this, they assault the del Moral residence, targeting Juana’s life. As a last ditch effort to bring the prince his bride, the San Maltilia Airforce hires a mercenary of mixed blood—a bestado—to fly Juana to the Levamme capital in secret. The pilot, Charles, accepts the mission…but traversing an ocean alone, into enemy territory, proves a much more dangerous ordeal than anyone could have anticipated. (Source: NIS America)
A group of enigmatic white-haired children has been spotted at different times and places in Europe for over 500 years. Always with the appearance of 11-year-olds, they behave far more mature than they should be, never grow old, and seem to have supernatural power. What they have been seeking is a girl, and the only clue they have is a picture with a crescent moon. Now, in the year of 2012, an athletic boy named Tohma is about to be involved in this centuries-long mystery. (Source: ANN)
One year has passed since the Black Rebellion, a failed uprising against the Holy Britannian Empire led by the masked vigilante Zero, who is now missing. At a loss without their revolutionary leader, Area 11’s resistance group—the Black Knights—find themselves too powerless to combat the brutality inflicted upon the Elevens by Britannia, which has increased significantly in order to crush any hope of a future revolt.
Lelouch Lamperouge, having lost all memory of his double life, is living peacefully alongside his friends as a high school student at Ashford Academy. His former partner C.C., unable to accept this turn of events, takes it upon herself to remind him of his past purpose, hoping that the mastermind Zero will rise once again to finish what he started, in this thrilling conclusion to the series. [Written by MAL Rewrite]
Set in a continent divided into two commonwealths that have been engaged in war for hundreds of years, Allison and Will go on a mission to search “the treasure that will put an end to the war”. Their hope is inherited to their daughter Lillia, who strives to thaw the torn nations into a united country. This anime encourages young generations to believe in a world without hatred or war regardless of nationalities and beliefs. (Source: Anime Network)
In the peaceful theocracy of Simulicram, everyone is born female. At age 17, each maiden undergoes a special ceremony where she chooses her sex. However, only Pairs of maiden priestesses can synchronize with the ancient flying ships known as Simoun needed to defend Simulicram. These Pairs refrain from undergoing the ceremony as long as they wish to keep piloting their Simoun.
Aer is recruited to be a Simoun pilot after a terrifying attack by an enemy nation decimates the squadron known as Chor Tempest. To earn her wings she needs to find her way into the heart of Neviril, Regina of Chor Tempest. But Neviril’s heart still belongs to her previous Pair, lost in the battle when she attempted a forbidden Simoun maneuver.(Source: Media Blasters)
The story centers around a spirited high school girl named Marika. She keeps herself busy with the space yacht club and her part-time job at a high-class retro café. One day, two strangers suddenly appear and claim to be subordinates of her dead father. They demand that she assume command of the space pirate ship Bentenmaru. A privateer ship’s compact was made during a war of independence a century ago, and according to that compact, the ship must be inherited by the captain’s next direct descendant. Marika finds herself embarking on a new life as a space pirate. (Source: MyAnimeList)
After her single mother decides to run off with a boyfriend to dodge debt collectors, the young and energetic Ohana is sent to live with her grandmother. However, her grandmother is the strict owner of a hot springs inn and requires her to work at the inn to pay for her living expenses. Although Ohana is unhappy about this situation at first, she decides to make the best of her situation and work hard. Ohana’s life is suddenly filled with fun, mischief, and drama! [Written by MAL Rewrite]
It is the year After Colony 195, and war between the Space Colonies and Earth has begun. To give the colonies an edge, they send 5 young soldiers, trained to perfection, to earth in the most powerful of Mobile Suits-Gundams. With their arrival, the tide of the war changes as they battle against the Earth forces and the Colonies of their origin. (Source: ANN)
References: MyAnimeList, Wiki, ANN